Note:
The scheduled time is 15-20 minutes for communication and 30 minutes (plus extra 15 minutes if needed) for lectures. Facilities will be provided for slide projector, overhead projector, multimedia projector.

Thursday, November 7th, 2002 – 17.00 (or 17.30)

Welcome
by W. Agnieszka Fogel,
President of the Polish Histamine Research Society

Presentation of the Honorary Membership of the Polish Histamine Research Society
To Professor Madeleine Ennis, The Queen˙s University of Belfast
„Human lung mast cells” – Conference lecture by Prof. Madeleine Ennis

18.30 Festive Dinner

Friday, November 8th, 2002

9.00 – 11.30
session 1: Amine Receptors
Chair Person: Katarzyna Kieć-Kononowicz

Lectures & free communications:

W. Schunack et al.
Freie Universität Berlin, Germany
„New highly potent and selective ligands for histamine receptor subtypes”

E. Schlicker et.al
Department of Pharmacology and Toxicology, University of Bonn, Germany
„New tools for the histaminologist: potent H1-receptor agonists and imidazole and non-imidazole H3-receptor ligands”

Łażewska D. 1, Kieć-Kononowicz K. 1, Elz S.2, Pertz H. H.3, Stark H.4 and Schunack W.3
1 Medical College, Jagiellonian University, Poland,
2 Universität Regensburg,
3 Freie Universität Berlin,
4 Johann Wolfgang Goethe-UniversitätFrankfurt, Germany
„Can oxygen be a bioisoster for the methylene group? – investigation of histamine H3-receptor antagonists of n-phenoxyalkyl carbamate derivatives of 3-(n-piperidino)propanol”

K. Kieć-Kononowicz 1, M. Więcek* 1, X. Ligneau 2, J.-C. Schwartz 3 H. Stark 4 and W. Schunack 5
1 Jagiellonian University, Medical College, Department of Chemical Technology of Drugs, Cracow, Poland;
2 Laboratoire Bioprojet, Paris, France;
3 Centre Paul Broca de l’INSERM, Paris, France,
4 Johan Wolfgang Goethe-Universität, Frankfurt, Germany,
5 Institut für Pharmazie, Freie Universität Berlin, Berlin, Germany;
„N-alkyl carbamates of 3-(1H-imidazole)-4-YL propanol: antagonist properties at human histamine H3 receptors”

J. Danowski, H. Gendek-Kubiak, B. L. Kmieć
Chair of Histology and Embryology, Medical University, ŁódŸ, Poland
„Histochemical investigations of the guinea pigs’ parathyroid glands after the histamine and histamine receptor blockers application”

B. Malinowska1, K. Kieć-Kononowicz2, G.Godlewski1, U. Szymańska1, E. Schlicker3
1 Department of Experimental Physiology, Medical Academy in Białystok, Poland,
2 Department of Chemical Technology of Drugs, Jagiellonian University Medical College, Krakow, Poland,
3 Department of Pharmacology and Toxicology, University of Bonn
„Influence of bupranolol analogues on atypical cardiostimulant β-adrenoceptors in pithed rats.”

U. Szymańska1, H. Kozłowska1, E. Schlicker2, B. Malinowska1
1 Department of Experimental Physiology, Medical Academy in Białystok, Poland,
2 Department of Pharmacology and Toxicology, University of Bonn, Germany
„Involvement of atypical β-adrenoceptors in the relaxation of the rat mesenteric artery”
Coffee break

11.45 – 12.45
Session 2: Synthesis of histamine
Chair Person: Sławomir Maœliński

Lectures & free communications:

S. Tanaka & A. Ichikawa
Department of Physiological Chemistry, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan
„Regulation of l-histidine decarboxylase expression in mast cells”

W. Wagner, A. Ichikawa, S. Tanaka, P. Panula, W.A. Fogel
Institute of Biogenic Amines, Polish Academy of Sciences, Lodz, Poland;
Department of Physiological Chemistry, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan;
Department of Biology, Abo University, Finland
„Localisation of histamine and histidine decarboxylase possessing cells of murine mammary gland”

E.Wojtecka-Łukasik1, A.Marton*1, D.Maœlińska2, S.Maœliński1, 2
1 Department of Biochemistry, Institute of Rheumatology,
2 Department of Developmental Neuropathology, Polish Academy of Sciences, 3 Department of Pathophysiology, Medical Academy, Warsaw, Poland
„Effect of cryotherapy on adjuvant arthritis in the rat”
Lunch

14.00 – 16.15
Session 3: Metabolism of biogenic amines and polyamines
Chair Person: W. A. Fogel

Lectures & free communications:

Hubert G. Schwelberger
Labor für Theoretische Chirurgie, Universitätsklinik für Chirurgie, University of Innsbruck, Austria
„Inactivation of histamine”

P. Pietrangeli & B. Mondovì*
Department of Biochemical Sciences „A Rossi Fanelli” and C.N.R. Centre of Molecular Biology, University of Rome „La Sapienza”, Rome, Italy
„Possible role of amine oxidases in cell growth and differentiation”

S. Beninati* & A. Lentini
Department of Biology, University Tor Vergata, Rome, Italy
„Catabolic oxidation of γ -glutamyl-polyamines”

P. Socha*, W.A. Fogel, K. Sasiak, I. Jankowska, M. Adamowicz, J. Pawłowska, J. Socha
The Children’s Memorial Health Institute, Warsaw & Institute of Biogenic Amines, Polish Academy of Sciences, Lodz, Poland
„Erythrocyte polyamine concentration as an indicator of liver regeneration in children with chronic cholestasis”

B. Skrzydło-Radomańska, W. Kosikowski, K. Laskowska, J. Schabowski, H. Cichoż-Lach
Gastroenterology Clinic, Medical Academy, Lublin, Poland
„Influence of short and long-term therapy with proton pomp inhibitor on serotonin and its metabolism in rat’s large bowel; comparison with H2 blockers therapy.”

17.30 Dinner

19.00 Concert

Lodz Philharmony, Piotrkowska 243
Serie: Great Virtuoso – Great Personality
Soloist Jakub Jakowicz – Violin
Symphonic Orchestra, director: Marek Pijarowski
K. Penderecki – Adagietto from „The Lost Paradise”
J. Sibelius – Violin concert d-moll op. 47

Saturday, November 9th, 2002

9.30 – 10.50
Session 4: Histamine and CNS
Chair Person: Barbara Malinowska

Lectures & free communications:

L.Tuomisto
Department of Pharmacology & Toxicology, University of Kuopio, Finland
„Histamine and epilepsy”

A. Yamatodani
Laboratory of Pharmacology, Department of Medical Physics, School of Allied Health Sciences, Faculty of Medicine, Osaka University, Japan
„Brain histamine and feeding: a microdialysis study”

G. Królczyk , D. Żurowski, A. Ziomber, PJ. Thor
Department of Pathophysiology, Medical College, Jagiellonian University, Cracow, Poland
„Low frequency vagal afferent neuromodulation suppresses food intake via its central effects”
Coffee break

11.45 – 12.45
Session 5: Mast cell
Chair Person: Janina Wyczółkowska

Lectures & free communications:

J. Dastych*1,2, A. Walczak-Drzewiecka2, V. Adamczewska1, D. Trzaska1, Maciej Olszewski1, Janina Wyczółkowska2
1 International Institute of Molecular and Cell Biology in Warsaw,
2 Institute of Biogenic Amines Polish Academy of Sciences, Lodz, Poland
„PostTranscriptional Mechanisms regulating cytokine Expression in mast cells”

Khalid N.I. Al-Nedawi(1), Janusz Szemraj(2), Radoslaw Bednarek(1), Maria Swiatkowska(3), Jaroslaw Dastych(4) , Janina Wyczolkowska(1)
1 Department of Biogenic Amines, Polish Academy of Sciences, 2 Department of Biochemistry, Medical University of Lodz, 3 Department of Molecular and Medical Biophysics, Medical University of Lodz, 4 International Institute of Molecular and Cell Biology, Warsaw, Poland
„Thymosin β4 activates Plasminogen Activator Inhibitor-1. Possible role of MAPK and AP-1 transcription factors”

G Szewczyk*, D Szukiewicz, J Sokolowski, A Szewczyk, S Maslinski
Laboratory of Placental Research, Department of General & Experimental Pathology, University School of Medicine, Warsaw, Poland
„Localisation of mast cells within placental vascular network in preeclampsia – preliminary study”

D. Szukiewicz*, D. Maslinska, G. Szewczyk, J. Stelmachow
Lab. of Placental Research, Dept. General & Experimental Pathology and 1st Dept. Obstet. & Gynecology, 2nd Faculty of Medicine, University School of Medicine, Warsaw, Poland
„Administration of bioactive natriuretic peptides and histamine release in the placental circulation”

R. Nosal
Institute of Experimental Pharmacology Slovak Academy of Sciences, Bratislava, Slovakia
„Free radicals and histaminergic system”
Farewell

Lunch

14.00 Visit to Łódź (optional)
19.00 Farewell Dinner by WAF: Kwarcowa 102

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